Found 9 matching trials
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1) PHASE2 A Phase 2 multi-center open-label basket trial of nab-sirolimus for adult a...
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Active Not Recruiting
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A Study to testABI-009 in Patients With Metastatic, Unresectable, Low or Intermediate Grade Neuroendocrine Tumors of the Lung or Gastroenteropancreatic System PHASE2 The purpose of this study is to determine whether ABI-009 will make advance...
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Ochsner Clinic Foundation
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Phase 1/2 Study of ABI-009 in Nonmuscle Invasive Bladder Cancer PHASE1 Purpose of this study is to determine appropriate dosing of ABI-009 and eva...
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Columbia University Medical Center
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Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors PHASE1 This phase I trial studies the side effects and best dose of nanoparticle a...
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Children's Hospital of Alabama
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ABI-009 (Nab-sirolimus) in Patients With Genetically-confirmed Leigh or Leigh-like Syndrome PHASE2 A phase 2a, open-label study to evaluate the safety, tolerability, and clin...
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Multiple Locations
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Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas PHASE1 This phase I/II trial studies the side effects and best dose of nab-sirolim...
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Fred Hutch/University of Washington Cancer Consortium
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Expanded Access for ABI-009 in Patients With Advanced PEComa and Patients With a Malignancy With Relevant Genetic Mutations or mTOR Pathway Activation N/A Expanded Access for an Intermediate-size Population for ABI-009 (Sirolimus ...
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Multiple Locations
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Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial PHASE1 This phase Ib trial determines if samples from a patient's cancer can be te...
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OHSU Knight Cancer Institute
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Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations EARLY_PHASE1 This pilot trial studies how well nanoparticle albumin-bound rapamycin work...
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Mayo Clinic in Arizona
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